Long-term complications of continent catheterizable channels: a problem for transitional urologists.

A majority of the transitional urology patient population have neurogenic bladder and many of these patients have undergone creation of continent catheterizable channels (CCCs) to facilitate bladder emptying. Transitional urologists will be faced with revision of these channels due to a variety of possible complications. We performed a comprehensive literature review to the data regarding the incidence, timing, and predisposing factors that lead to complications of CCCs as well as surgical revision techniques and their outcomes. Long-term channel complications and related revisions are common (25-30%) and likely underestimated. While many predictors for revision have been posited, the only predictor that has been significant in robust multivariable analysis is channel type, with appendicovesicostomies having a lower chance of requiring revision compared to Monti channels. Channels created in adults have high likelihood of requiring revision, even within a relatively short follow-up period. We review techniques for management of channel complications and their outcomes. As patients with congenital urologic conditions requiring CCCs are gaining longer lifespans, transitional urologists will be faced with revision and/or replacement of these channels. While some of these patients may require supravesical diversion in the future, data show that revision is feasible with good outcomes. Longer-term follow-up data is needed to understand the life-span and best practices of new CCCs created among the transitional population

Crystalline Silicates in Comets: Modeling Irregularly-Shaped Forsterite Crystals and Its Implications on Condensation Conditions

Crystalline silicates in comets are a product of the condensation in the hot inner regions (T > or approx. equals 1400 K [1]) of our proto-planetary disk or annealing at somewhat lower temperatures (T > or approx. equals 1000-1200 K) [2, 3, 4] in shocks coupled with disk evolutionary processes that include radial transport of crystals from their formation locations out to the cold outer regions where comet nuclei formed. The grain shape of forsterite (crystals) could be indicative of their formation pathways at high temperatures through vapor-solid condensation or at lower temperatures through vapor-liquid-solid formation and growth [5, 6, 7]. Experiments demonstrate that crystals that formed from a rapidly cooled highly supersaturated silicate vapor are characterized by bulky, platy, columnar/needle and droplet shapes for values of temperature and supersaturation, T and sigma, of 1000-1450 C and 230, respectively [7]. The experimental columnar/needle shapes, which form by vapor-liquid-solid at lower temperatures (<820 C), are extended stacks of plates, where the extension is not correlated with an axial direction: columnar/needles may be extended in the c-axis or a-axis direction, can change directions, and/or are off-kilter or a bit askew extending in a combination of the a- and c-axis direction

Remote-sensing Characterisation of Major Solar System Bodies with the Twinkle Space Telescope

Remote-sensing observations of Solar System objects with a space telescope offer a key method of understanding celestial bodies and contributing to planetary formation and evolution theories. The capabilities of Twinkle, a space telescope in a low Earth orbit with a 0.45m mirror, to acquire spectroscopic data of Solar System targets in the visible and infrared are assessed. Twinkle is a general observatory that provides on demand observations of a wide variety of targets within wavelength ranges that are currently not accessible using other space telescopes or that are accessible only to oversubscribed observatories in the short-term future. We determine the periods for which numerous Solar System objects could be observed and find that Solar System objects are regularly observable. The photon flux of major bodies is determined for comparison to the sensitivity and saturation limits of Twinkle's instrumentation and we find that the satellite's capability varies across the three spectral bands (0.4-1, 1.3-2.42, and 2.42-4.5{\mu}m). We find that for a number of targets, including the outer planets, their large moons, and bright asteroids, the model created predicts that with short exposure times, high-resolution spectra (R~250, {\lambda} 2.42{\mu}m) could be obtained with signal-to-noise ratio (SNR) of >100 with exposure times of <300s

Small Bodies Science with Twinkle

Twinkle is an upcoming 0.45m space-based telescope equipped with a visible and two near-infrared spectrometers covering the spectral range 0.4 to 4.5{\mu}m with a resolving power R~250 ({\lambda}<2.42{\mu}m) and R~60 ({\lambda}>2.42{\mu}m). We explore Twinkle's capabilities for small bodies science and find that, given Twinkle's sensitivity, pointing stability, and spectral range, the mission can observe a large number of small bodies. The sensitivity of Twinkle is calculated and compared to the flux from an object of a given visible magnitude. The number, and brightness, of asteroids and comets that enter Twinkle's field of regard is studied over three time periods of up to a decade. We find that, over a decade, several thousand asteroids enter Twinkle's field of regard with a brightness and non-sidereal rate that will allow Twinkle to characterise them at the instrumentation's native resolution with SNR > 100. Hundreds of comets can also be observed. Therefore, Twinkle offers researchers the opportunity to contribute significantly to the field of Solar System small bodies research.Comment: Published in JATI

The Dream System in \u3ci\u3eThe Lord of the Rings\u3c/i\u3e

Explores use of dreams in The Lord of the Rings for various purposes, especially as foreshadowing or reconstruction of events. Includes a lengthy appendix of occurrences of or reference to dreams or dreamlike conditions

Grant Application: Maine Partners For Health In Africa

IPEC Mini-grant application for funding of UNE student project Maine Partners for Health in Africa: Clinical and Public Health Initiatives. The team organized a day long conference in February 2014, The Maine Africa Connection, to bring together UNE community, Maine organizations, members of the public, and practitioners to discuss best practices, challenges, and begin new collaborations for future health projects. Goals of the conference were to gather experts on interdisciplinary approaches to health care for African refugees and immigrants in Maine, educate health providers, administrators, educators, and community members on best practices for refugee health care, and set a foundation for professional collaboration and leadership.https://dune.une.edu/minigrant_meafrica/1000/thumbnail.jp

Absorption Efficiencies of Forsterite. I: DDA Explorations in Grain Shape and Size

We compute the absorption efficiency (Qabs) of forsterite using the discrete dipole approximation (DDA) in order to identify and describe what characteristics of crystal grain shape and size are important to the shape, peak location, and relative strength of spectral features in the 8-40 {\mu}m wavelength range. Using the DDSCAT code, we compute Qabs for non-spherical polyhedral grain shapes with a_eff = 0.1 {\mu}m. The shape characteristics identified are: 1) elongation/reduction along one of three crystallographic axes; 2) asymmetry, such that all three crystallographic axes are of different lengths; and 3) the presence of crystalline faces that are not parallel to a specific crystallographic axis, e.g., non-rectangular prisms and (di)pyramids. Elongation/reduction dominates the locations and shapes of spectral features near 10, 11, 16, 23.5, 27, and 33.5 {\mu}m, while asymmetry and tips are secondary shape effects. Increasing grain sizes (0.1-1.0 {\mu}m) shifts the 10, 11 {\mu}m features systematically towards longer wavelengths and relative to the 11 {\mu}m feature increases the strengths and slightly broadens the longer wavelength features. Seven spectral shape classes are established for crystallographic a-, b-, and c-axes and include columnar and platelet shapes plus non-elongated or equant grain shapes. The spectral shape classes and the effects of grain size have practical application in identifying or excluding columnar, platelet or equant forsterite grain shapes in astrophysical environs. Identification of the shape characteristics of forsterite from 8-40 {\mu}m spectra provides a potential means to probe the temperatures at which forsterite formed.Comment: 55 pages, 15 figure

A New Framework for Network Disruption

Traditional network disruption approaches focus on disconnecting or lengthening paths in the network. We present a new framework for network disruption that attempts to reroute flow through critical vertices via vertex deletion, under the assumption that this will render those vertices vulnerable to future attacks. We define the load on a critical vertex to be the number of paths in the network that must flow through the vertex. We present graph-theoretic and computational techniques to maximize this load, firstly by removing either a single vertex from the network, secondly by removing a subset of vertices.Comment: Submitted for peer review on September 13, 201